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Nuscript; RP: analysis and interpretation of data, critical review of the manuscript; SB: critical review of the manuscript; AFF: acquisition of data; RC: acquisition and interpretation of CT images; SB: acquisition and interpretation of CT images; MC: have given final approval ofFaustino et al. BMC Cardiovascular Disorders 2014, 14:2 http://www.biomedcentral.com/1471-2261/14/Page 10 of13.14.15. 1

Rogen receptor predict response to tamoxifen treatment in patients with recurrent breast cancer: a retrospective study. Clin Cancer Res 2005, 11:7311-7321. 17. Dorssers LC, van Agthoven T, Brinkman A, Veldscholte J, Smid M, Dechering KJ: Breast cancer oestrogen independence mediated by BCAR1 or BCAR3 genes is transmitted through mechanisms distinct from the oestrogen receptor signalling pathway or

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Ine for WHO 4 events eventually judged not to meet predefined protocol criteria by the ERC, leading to a total 207/314 (66 ) switches in CDM being for WHO 4 events. In the same period, 70 multiple (within 60 days) and 392 single WHO 3 events were reported in participants not switching forCD4.250 Predicts HIV VL,400 in Failing AdultsTable 1. Reasons for not switching when first met immunological/cl

Point-of-care assay, would capture most individuals without virological failure, for whom switching could be premature and unnecessary.ROC area under the curve for CD4 predicting VL,400 copies/ml0.91**0.0.0.90 p = 0.81,Patients monitored clinically with 12-weekly CD4 but no VL results1656 LCM participants initiated ART with median(IQR) CD4 86(32?40) cells/mm3 and were clinically monitored together

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