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Either ESR1-positive and/or ESR2-low pT1 tumors.Introduction Estrogens influence the aggressiveness of breast cancer through their cognate nuclear receptors. In particular, the estrogen receptor-alpha (ERa) (ESR1) - present in tumor cells of about 70 to 75 of all breast tumors is considered crucial because of its proliferationinducing actions and for that reason is an important target for therap

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1st, you need to realize what cashmere is and why men and women want it. Cashmere is distinct from typical sheep's wool. It is finer, softer, and up to eight moments hotter than regular wool. The greatest cashmere in the world comes from Mongolia. The cold dry local weather and large elevation in Mongolia are excellent for producing the most luxurious cashmere on the planet. The cashmere is truly

Ing administration of rifabutin 300 mg once daily (Treatment A, #) or rifabutin 300 mg once daily plus SQV-SGC 1200 mg three times daily (Treatment C, ).treatment was greater (33 ) compared to when coadministered with saquinavir (21 ). The within patient variability was approximately 29 .Effects of rifabutin on saquinavirpharmacokineticsThe mean ( CV) AUC(0,8 h), Cmax and C8 for saquinavir when a

Nd multivariable analysis higher DC-SCRIPT levels were associated with a favorable outcome for both the entire cohort and patients with lymph node-negative (LNN) disease that did not receive adjuvant therapy (DFS, MFS and OS; all, P

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Programme): an international survey. Lancet 2002, 360:1631?639. Rutten FH, Grobbee DE, Hoes AW: Differences between general practitioners and cardiologists in diagnosis and management of heart failure: a survey in every-day practice. Eur J Heart Fail 2003, 5:337?44. Rostagno C, Olivo G, Comeglio M, Boddi V, Banchelli M, Galanti G, et al: Prognostic value of 6-minute walk corridor test in patients