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Nversion to determine whether there were differences in ulcer occurrence by randomization group in the absence of study drug. All analyses were conducted in SAS 9.3 or Stata 12.Results Study participantsCharacteristics of the 2,499 iPrEx participants have been described previously. [13] Briefly, all participants were born male and 313 (13.0 ) identified as transgender or as women. The mean age at
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Espite successful HCV eradication. Other complications such as development of carcinoma may be more readily amenable to more rapid risk reduction with antiviral therapy. Further studies with long periods of follow-up will be needed to address these questions. Our study has several limitations. Not all patients had measures of immune activation documented in their study records and were therefore e
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The previous 2011 Malawian guidelines, we estimated that 80.0 (95 CI 77.6 to 82.3) of the HIV-positive population was in need of ART at the time of the survey (Table 2). The WHO 2013 ART guidelines, which were implemented in 2014 in Malawi (raising the CD4 threshold from 350 to 500 CD4 cells/mL), increased eligibility to 87.5 (95 CI 85.5 to 89.4) and decreased ART coverage from 80.5 (77.8 to
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Ain lesions without Ab deposits. They include multiple sclerosis plaques [111] as well as lesions of adrenoleukodystrophy, DRPLA, and ischemic strokes [115]. Ab was also shown to induce CD40 expression by cultured microglia [116,117] and cultured vascular endothelial cells [116,118][118-120]. HIV-1 induces the latter phenomenon as well [121] It may be the mechanism by which CD40 expression is up-r
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